Micron, The International Research and Review Journal for Microscopy, has published a paper by Tanaka et Al, which reports “the development of a direct point electron beam irradiation system to investigate the biological functions of subcellular domains in a living cell”
Silson’s 50nm silicon nitride membranes separated the atmospheric and the high vacuum environment for the direct point electron beam (DPEB) irradiation; “the focused electron beam penetrated the membrane and formed a nano electron spot whose radius can be down to only a few tens of nanometer at the surface”
The abstract concludes: “Point electron beam exposure is expected to be employed for various cellular stimulation protocols, and this enables the investigation of the biological functions of subcellular domains”
Follow this link to read more about this fascinating direct point electron beam research!